Auditory Fine-Tuned Suppressor of TMS-Clicks (TMS-Click AFTS): A Novel, Perceptually Driven/Tuned Approach for the Reduction in AEP Artifacts in TMS-EEG Studies

نویسندگان

چکیده

TMS contaminates concurrent EEG recordings with Auditory Evoked Potentials (AEPs), which are caused by the perceived impulsive acoustic noise of coils. We hereby introduce a novel and perceptually motivated/tuned method for suppression auditory evoked artifacts rTMS under name “Auditory Fine-Tuned Suppressor TMS-Clicks” (TMS-click AFTS). The proposed is based on deployment psychophysically-matched wide-band (WBN) masking stimulus, whose parametric synthesis presentation upon adaptive psychophysical optimization. stimulus constructed individually each patient/subject, thus facilitating aspects precision medicine. A specially designed automation software used realization an procedure optimal parameterization level, optimizing both subject’s comfort degree AEP reduction. also takes into account combined effect intensity level can as well any possibly available hearing acuity data. To assess efficacy in reducing effects TMS, we performed TMS-EEG 60 channel TMS-compatible system cohort healthy subjects (n = 10) patients epilepsy four conditions (i.e., resting without mask sham at various levels). approach shows promising results terms efficiency warrants further investigation research clinical settings.

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ژورنال

عنوان ژورنال: Applied sciences

سال: 2023

ISSN: ['2076-3417']

DOI: https://doi.org/10.3390/app13021047